Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16916948 | 0.83 | PIK3C3 (0.48) | ABL1BCRPIK3C3HTR6 | |
| SCHEMBL2128761 | 0.81 | ABL1 (0.45) | ABL1BCRHTR6ALDH1A1HTT | |
| SCHEMBL14321207 | 0.80 | HTR6 (0.42) | ABL1BCRHTR6ALDH1A1LMNA | |
| SCHEMBL31279422 | 0.80 | HTR6 (0.42) | ABL1BCRHTR6ALDH1A1LMNA | |
| SCHEMBL16923725 | 0.79 | PIK3C3 (0.34) | PIK3C3HTR6 | |
| SCHEMBL16923795 | 0.79 | PIK3C3 (0.37) | PIK3C3HTR6HTT | |
| SCHEMBL16923720 | 0.73 | PIK3C3 (0.46) | PIK3C3HTR6 | |
| SCHEMBL16475117 | 0.72 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL19278217 | 0.71 | ALDH1A1 (0.35) | ABL1BCRALDH1A1LMNAHTT | |
| SCHEMBL2369513 | 0.70 | PARP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017143291-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2017-08-24 | — | — | WO | disclosed |