Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.35 |
| ▸ | CDK9 | P50750 | 8/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31279283 | 0.88 | IKZF1 (0.42) | IKZF1PARP1IKZF2CCNT1CDK9 | |
| SCHEMBL31279571 | 0.87 | IKZF1 (0.41) | IKZF1PARP1IKZF2CCNT1CDK9 | |
| SCHEMBL31279902 | 0.86 | IKZF1 (0.46) | IKZF1PARP1IKZF2DRD2DRD4 | |
| SCHEMBL31279413 | 0.86 | PARP1 (0.39) | IKZF1PARP1IKZF2CCNT1CDK9 | |
| SCHEMBL31279172 | 0.85 | IKZF1 (0.44) | IKZF1PARP1IKZF2CCNT1CDK9 | |
| SCHEMBL31280365 | 0.85 | IKZF1 (0.43) | IKZF1PARP1IKZF2DRD2DRD4 | |
| SCHEMBL31280019 | 0.83 | CCNT1 (0.39) | IKZF1PARP1CCNT1CDK9PRKAB2 | |
| SCHEMBL31279012 | 0.83 | DRD2 (0.40) | IKZF2DRD2DRD4DRD3 | |
| SCHEMBL31338347 | 0.82 | IKZF1 (0.66) | IKZF1IKZF2 | |
| SCHEMBL31279785 | 0.82 | IKZF1 (0.46) | IKZF1PARP1IKZF2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| CN-119451952-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2025-02-14 | — | — | CN | claimed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | claimed |
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| CN-119451952-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |