Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280317 | 0.91 | DRD2 (0.35) | DRD2CRBNIKZF3HTR1AHTR2A | |
| SCHEMBL31278698 | 0.91 | CRBN (0.37) | DRD2CRBNIKZF3HTR1AHTR2A | |
| SCHEMBL31280244 | 0.88 | DRD2 (0.37) | DRD2CRBNIKZF3HTR1AHTR2A | |
| SCHEMBL31278518 | 0.87 | ALDH1A1 (0.38) | DRD2CRBNIKZF3HTR1AHTR2A | |
| SCHEMBL31279743 | 0.86 | LMNA (0.37) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL31279168 | 0.86 | DRD2 (0.39) | DRD2CRBNIKZF3DRD4DRD3 | |
| SCHEMBL31279051 | 0.86 | IKZF2 (0.36) | DRD2CRBNIKZF3HTR1AHTR2A | |
| SCHEMBL31279424 | 0.86 | DRD2 (0.38) | DRD2CRBNIKZF3HTR1AHTR2A | |
| SCHEMBL31280037 | 0.85 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD4HTR2C | |
| SCHEMBL31279771 | 0.85 | DRD2 (0.39) | DRD2CRBNIKZF3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | claimed |
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |