Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.56 |
| ▸ | PDE4A | P27815 | 15/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133694 | 0.88 | PDE4B (0.51) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL3120558 | 0.85 | PDE4B (0.49) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL3200134 | 0.84 | SLC6A2 (0.43) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL3132196 | 0.80 | PDE4B (0.49) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL3126024 | 0.80 | PDE4D (0.43) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6466878 | 0.79 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL3129210 | 0.78 | PDE4D (0.43) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL1157408 | 0.77 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL30352612 | 0.76 | PDE4B (0.62) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL22713868 | 0.76 | PDE4B (0.62) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |