Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129614 | 0.86 | PDE4B (0.40) | KDM4EALDH1A1MAPK1NPSR1PDE4B | |
| SCHEMBL3126024 | 0.86 | PDE4D (0.43) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL3127976 | 0.84 | PDE4D (0.56) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3123524 | 0.84 | PDE4D (0.49) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL3129210 | 0.84 | PDE4D (0.43) | SLC6A2SLC6A4KDM4EALDH1A1MAPK1 | |
| SCHEMBL3131252 | 0.83 | ATM (0.41) | KDM4EMAPK1NPSR1ALPLPDE4B | |
| SCHEMBL3130706 | 0.79 | AAK1 (0.39) | KDM4EMAPK1NPSR1PDE4BPDE4D | |
| SCHEMBL3201429 | 0.75 | PDE4B (0.38) | KDM4EALDH1A1MAPK1NPSR1PDE4B | |
| SCHEMBL3117907 | 0.75 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDMAPK1NPSR1 | |
| SCHEMBL3122742 | 0.75 | L3MBTL1 (0.50) | SLC6A2SLC6A4KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE4B, PDE3B | SLC6A2 1188/4885SLC6A4 254/4885KDM4E 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.