Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.55 |
| ▸ | PDE4A | P27815 | 12/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469942 | 0.85 | PDE4D (0.48) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL1157930 | 0.80 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL2926106 | 0.80 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL3127976 | 0.79 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL1157762 | 0.78 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL6532820 | 0.76 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2930583 | 0.75 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL1157297 | 0.74 | PDE4D (0.54) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL3120236 | 0.73 | PDE4D (0.58) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL6528128 | 0.73 | ALDH1A1 (0.41) | PDE4DPDE4BPDE4APDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569908-A2 | PYRIDINE N-OXIDE COMPOUNDS AS PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceutical Corporation (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2004046113-A2 | PYRIDINE N-OXIDE COMPOUNDS AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | claimed |
| EP-1569908-A2 | PYRIDINE N-OXIDE COMPOUNDS AS PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceutical Corporation (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004046113-A2 | PYRIDINE N-OXIDE COMPOUNDS AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |