SCHEMBL3128015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3128012	1.00	ALDH1A1 (0.43)	ALDH1A1EPHX1EPHX2ITKPTPN1
	SCHEMBL15576245	0.88	ALDH1A1 (0.43)	ALDH1A1EPHX1EPHX2ITKPTPN1
	SCHEMBL2150845	0.81	ALDH1A1 (0.48)	ALDH1A1EPHX1EPHX2PTPN1RXFP1
	SCHEMBL27821328	0.80	ALDH1A1 (0.37)	ALDH1A1EPHX1EPHX2ITKPTPN1
	SCHEMBL21799837	0.77	APP (0.44)	ALDH1A1EPHX1EPHX2ITKPTPN1
	SCHEMBL29922690	0.77	APP (0.44)	ALDH1A1EPHX1EPHX2ITKPTPN1
	SCHEMBL13379511	0.77	DDB1 (0.43)	EPHX1EPHX2PTPN1RXFP1AOC1
	SCHEMBL3128334	0.76	ALDH1A1 (0.55)	ALDH1A1PTPN1
	SCHEMBL3122061	0.76	BRD4 (0.42)	ALDH1A1HDAC4HDAC3HDAC1HDAC2
	SCHEMBL3122069	0.76	BRD4 (0.42)	ALDH1A1HDAC4HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.