Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012186 | 0.87 | SLC6A4 (0.56) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL3524276 | 0.85 | SLC6A4 (0.54) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL3524278 | 0.85 | SLC6A4 (0.54) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25394251 | 0.81 | CTSL (0.49) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL26250851 | 0.81 | CTSL (0.49) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL27730411 | 0.81 | SLC6A2 (0.52) | HTR3ASLC6A4SLC6A2SLC6A3EPHX2 | |
| Trifluoroacetic Acid SCHEMBL20958365 | 0.79 | SLC6A4 (0.73) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL20958333 | 0.79 | SLC6A4 (0.73) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL23149384 | 0.76 | SLC6A4 (0.44) | CHRNA7SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL23149380 | 0.76 | SLC6A4 (0.44) | CHRNA7SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |