Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20213117 | 0.96 | ALDH1A1 (0.42) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL20213115 | 0.96 | ALDH1A1 (0.42) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL17198688 | 0.91 | CA1 (0.48) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL18089732 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TP53SMN1; SMN2CA1CA2 | |
| SCHEMBL28706139 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TP53SMN1; SMN2CA1CA2 | |
| SCHEMBL30583780 | 0.85 | MEN1 (0.41) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL18266887 | 0.84 | PTGS2 (0.44) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL23819198 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL17601836 | 0.80 | CA1 (0.47) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 | |
| SCHEMBL23818597 | 0.78 | CA1 (0.52) | ALDH1A1LMNACYP3A4MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303359-B1 | NUCLEOTIDES FOR THE TREATMENT OF CANCER | IDENIX PHARMACEUTICALS LLC (US) | 2024-11-06 | — | — | EP | disclosed |