Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 13/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.47 |
| ▸ | TSHR | P16473 | 12/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30756403 | 0.84 | KDM4E (0.43) | MEN1KMT2AGAATP53MAPT | |
| SCHEMBL31280463 | 0.79 | ABL1 (0.49) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL27030232 | 0.76 | KDM4C (0.57) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL25703791 | 0.76 | KDM4C (0.57) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL16993397 | 0.75 | MAPT (0.65) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL25130650 | 0.74 | TSHR (0.45) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL29119713 | 0.74 | KDM4C (0.52) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL22892765 | 0.73 | NR3C1 (0.51) | KDM4CMEN1KMT2AMAPT | |
| SCHEMBL25131153 | 0.73 | APLNR (0.54) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30205616 | 0.73 | APLNR (0.54) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727941-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024255885-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |