Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31281100 | 0.81 | KIF11 (0.41) | GRM5KIF11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29425391 | 0.77 | KIF11 (0.46) | GRM5KIF11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31281215 | 0.77 | NUDT1 (0.34) | — | |
| SCHEMBL30564957 | 0.75 | NUDT1 (0.38) | GRM5 | |
| SCHEMBL25380637 | 0.75 | NUDT1 (0.38) | GRM5 | |
| SCHEMBL484469 | 0.74 | APP (0.33) | GRM5 | |
| SCHEMBL25379469 | 0.72 | NUDT1 (0.36) | — | |
| SCHEMBL1477690 | 0.69 | GRM5 (0.43) | GRM5 | |
| SCHEMBL2922495 | 0.69 | CYP2A6 (0.55) | GRM5 | |
| SCHEMBL30694380 | 0.69 | CYP2A6 (0.55) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137130-A | Inhibitors of MEK kinase | 金耐特生物制药公司 | 2024-12-13 | — | — | CN | disclosed |