SCHEMBL31281983

SCHEMBL31281983

Nc1cc2ccccc2c(N)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 6/20 0.48
HPGD P15428 5/20 0.48
TSHR P16473 4/20 0.48
CYP3A4 P08684 2/20 0.48
KEAP1 Q14145 1/20 0.48
HPRT1 P00492 1/20 0.45
HIF1A Q16665 2/20 0.44
CYP1B1 Q16678 1/20 0.44
KDM4E B2RXH2 4/20 0.44
POLB P06746 4/20 0.44
HTT P42858 2/20 0.44
RAD52 P43351 2/20 0.44
HTR2A P28223 1/20 0.43
TDP1 Q9NUW8 3/20 0.41
GLA P06280 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NQO2 P16083 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677653 1.00 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL29463710 1.00 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL12124161 0.83 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL29368234 0.81 HTR2A (0.54) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL1264430 0.81 HTR2A (0.54) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL3317872 0.81 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL8655957 0.79 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL3668935 0.79 CYP2A6 (0.45) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL3673336 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL3669260 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371013-A Quaternary ammonium salt and preparation method and application thereof 中国石油天然气股份有限公司 2025-01-28 CN claimed
CN-119371013-A Quaternary ammonium salt and preparation method and application thereof 中国石油天然气股份有限公司 2025-01-28 CN disclosed