SCHEMBL3669260

SCHEMBL3669260

Nc1cc2ccccc2c(Br)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
HSD17B10 Q99714 5/20 0.43
HPGD P15428 4/20 0.43
TSHR P16473 3/20 0.43
CYP3A4 P08684 1/20 0.43
KEAP1 Q14145 1/20 0.43
POLB P06746 5/20 0.42
HPRT1 P00492 1/20 0.41
KDM4E B2RXH2 4/20 0.40
HTT P42858 2/20 0.40
RAD52 P43351 2/20 0.40
HIF1A Q16665 2/20 0.39
CYP1B1 Q16678 1/20 0.39
HTR2A P28223 1/20 0.39
GLA P06280 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
NQO2 P16083 2/20 0.37
CASP1 P29466 2/20 0.37
CASP7 P55210 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30534528 0.83 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL5030388 0.83 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL29463710 0.79 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL677653 0.79 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL31281983 0.79 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL24703324 0.79 CYP2A6 (0.40) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL13601825 0.79 POLB (0.39) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL13601826 0.79 CYP1A2 (0.45) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL12124161 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL10611288 0.77 HTR2A (0.52) ALDH1A1HSD17B10HPGDTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101407493-B Organic material and use thereof in organic EL device UNIV TSINGHUA 2010-07-21 CN disclosed
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
CN-100556899-C A kind of electroluminescent organic material and application thereof TSINGHUA UNIV BEIJING WEIXINNU (CN) 2009-11-04 CN disclosed
CN-101407493-A Organic material and use thereof in organic EL device UNIV TSINGHUA (CN) 2009-04-15 CN disclosed
CN-1785984-A Organic electroluminous material and its application UNIV TSINGHUA (CN) 2006-06-14 CN disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed