Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 14/20 | 0.50 |
| ▸ | TAB1 | Q15750 | 14/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280931 | 0.83 | JAK2 (0.44) | ALDH1A1MAP2K1AXL | |
| SCHEMBL31070093 | 0.82 | MAP2K1 (0.43) | MAP3K7TAB1ALDH1A1MAP2K1AXL | |
| SCHEMBL21713015 | 0.82 | MAP2K1 (0.59) | ALDH1A1TSHRMAP2K1AXLKDM4E | |
| SCHEMBL30996123 | 0.77 | NTRK1 (0.40) | MAP3K7TAB1ALDH1A1MAP2K1AXL | |
| SCHEMBL30421434 | 0.77 | MAP2K1 (0.43) | MAP2K1AXL | |
| SCHEMBL13627414 | 0.75 | HASPIN (0.46) | MAP3K7TAB1MAP2K1AXL | |
| SCHEMBL27934700 | 0.75 | NTRK1 (0.49) | MAP3K7TAB1MAP2K1AXL | |
| SCHEMBL14406911 | 0.75 | NTRK1 (0.44) | MAP2K1AXLKDM4E | |
| SCHEMBL28202369 | 0.74 | NTRK1 (0.44) | MAP3K7TAB1MAP2K1AXLKDM4E | |
| SCHEMBL29589055 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAP2K1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080779-A | Pyrrolopyrimidine ITK inhibitors | 阿克拉瑞斯治疗股份有限公司 | 2024-12-06 | — | — | CN | disclosed |