Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24776656 | 1.00 | KMT2A (0.42) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL31283496 | 0.82 | MAPT (0.42) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL31284926 | 0.80 | ALDH3A1 (0.46) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL24776919 | 0.78 | KMT2A (0.40) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL31283486 | 0.78 | MAPT (0.40) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL24776516 | 0.75 | MAPK10 (0.40) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL31283810 | 0.75 | MAPK10 (0.40) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL31283767 | 0.74 | KMT2A (0.35) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL24776296 | 0.74 | MAPT (0.47) | KMT2AMAPTCYP2D6CYP1A2MAPK1 | |
| SCHEMBL31283928 | 0.74 | MAPT (0.47) | KMT2AMAPTCYP2D6CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024229253-A1 | METHODS AND TREATMENT OF VIRAL INFECTION CAUSED BY SARS-COV-2 WITH FUSED BICYCLIC HETEROCYCLIC COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2024-11-07 | — | — | WO | disclosed |