Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284883 | 1.00 | NOTUM (0.36) | NOTUMTMEM97SIGMAR1ACACBMALT1 | |
| SCHEMBL31284457 | 0.92 | NOTUM (0.45) | NOTUMACACBMALT1MAPTSMN1; SMN2 | |
| SCHEMBL31283914 | 0.86 | SIRT6 (0.41) | NOTUMACACBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31284595 | 0.82 | NOTUM (0.46) | NOTUMTMEM97SIGMAR1ACACBMALT1 | |
| SCHEMBL31285341 | 0.81 | NOTUM (0.46) | NOTUMACACBMALT1TP53MAPT | |
| SCHEMBL31285385 | 0.81 | NOTUM (0.46) | NOTUMACACBMALT1TP53MAPT | |
| SCHEMBL31284447 | 0.80 | NOTUM (0.45) | NOTUMACACBTP53MAPTSMN1; SMN2 | |
| SCHEMBL31285325 | 0.80 | NOTUM (0.45) | NOTUMACACBTP53MAPTSMN1; SMN2 | |
| SCHEMBL31284970 | 0.79 | NOTUM (0.51) | NOTUMTMEM97SIGMAR1MALT1MAPT | |
| SCHEMBL31283935 | 0.79 | NOTUM (0.44) | NOTUMTMEM97SIGMAR1ACACBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |