Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284595 | 0.89 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31285501 | 0.89 | NOTUM (0.49) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31285385 | 0.88 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31285341 | 0.88 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31285325 | 0.87 | NOTUM (0.45) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31284447 | 0.87 | NOTUM (0.45) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31284457 | 0.87 | NOTUM (0.45) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31284466 | 0.84 | SIRT6 (0.42) | NOTUMMAPTSMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL31284530 | 0.83 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL31285035 | 0.83 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |