Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | CEPT1 | Q9Y6K0 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284622 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454878 | 0.85 | MAPT (0.47) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454910 | 0.83 | CETP (0.44) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454967 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454956 | 0.81 | CETP (0.44) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL31284610 | 0.80 | FASN (0.44) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454912 | 0.80 | FASN (0.44) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454955 | 0.80 | MAPT (0.43) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454917 | 0.80 | FASN (0.43) | ALDH1A1KDM4ECETPDHODHHPGD | |
| SCHEMBL24454873 | 0.80 | FASN (0.42) | ALDH1A1KDM4ECETPDHODHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | claimed |