Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311136 | 0.86 | ABL1 (0.40) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL326091 | 0.85 | ABL1 (0.42) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL313081 | 0.84 | MAOB (0.38) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL312471 | 0.83 | AKR1B1 (0.40) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL312054 | 0.82 | MAOB (0.39) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL311904 | 0.81 | HPGD (0.40) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL312050 | 0.81 | KDM4E (0.44) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL312381 | 0.80 | HPGD (0.44) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL313540 | 0.80 | MAPT (0.41) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL312452 | 0.80 | MAOB (0.39) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |