Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503863 | 0.85 | GABRP (0.54) | CA2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3121506 | 0.84 | ALDH1A1 (0.46) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL3129950 | 0.83 | ALDH1A1 (0.41) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL1145511 | 0.79 | PIK3CD (0.42) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL5758401 | 0.79 | PIK3CD (0.42) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL20489229 | 0.79 | PIK3CD (0.39) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL29995663 | 0.79 | PIK3CD (0.39) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL13180189 | 0.77 | KDM4E (0.41) | CA2PIK3CDPIP5K1CPIK3CBPI4KA | |
| SCHEMBL3126015 | 0.75 | GABRP (0.42) | CA2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2643755 | 0.75 | PIK3CD (0.39) | CA2PIK3CDPIP5K1CPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |