Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286711 | 0.90 | SCN9A (0.44) | SCN9ACACNA1HDRD2HRH1SIGMAR1 | |
| SCHEMBL20572924 | 0.83 | USP2 (0.43) | SCN9ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24809231 | 0.83 | MEN1 (0.46) | SCN9AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31286849 | 0.83 | HRH1 (0.41) | MEN1KMT2AHRH1 | |
| SCHEMBL31286870 | 0.81 | SCN9A (0.44) | SCN9AMEN1KMT2AGAAMAPT | |
| SCHEMBL20305593 | 0.81 | SCN9A (0.43) | SCN9ADRD2MEN1KMT2AHRH1 | |
| SCHEMBL6450457 | 0.81 | CHRM2 (0.38) | CACNA1HDRD2MEN1KMT2ANPC1 | |
| SCHEMBL7604209 | 0.81 | USP2 (0.43) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL15874982 | 0.81 | MEN1 (0.46) | SCN9AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30097332 | 0.81 | MEN1 (0.46) | SCN9AMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025022093-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2025-01-30 | — | — | WO | disclosed |