Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.59 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287844 | 0.84 | KDM4E (0.61) | LGALS8LGALS3KMT2AFLT3KDM4E | |
| SCHEMBL31287810 | 0.81 | KMT2A (0.67) | LGALS8LGALS3KMT2AFLT3KDM4E | |
| SCHEMBL378196 | 0.78 | SMAD3 (0.66) | KMT2AFLT3KDM4EHPGDHSD17B10 | |
| SCHEMBL31287938 | 0.78 | F7 (0.62) | LGALS8LGALS3KMT2AFLT3KDM4E | |
| SCHEMBL31287858 | 0.78 | KMT2A (0.78) | LGALS8KMT2AFLT3KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6919627 | 0.77 | SMAD3 (0.64) | KMT2AFLT3KDM4EHPGDHSD17B10 | |
| SCHEMBL31287879 | 0.75 | F7 (0.65) | LGALS8LGALS3KMT2AFLT3KDM4E | |
| SCHEMBL31287874 | 0.75 | LGALS8 (0.62) | LGALS8LGALS3KMT2AFLT3KDM4E | |
| SCHEMBL9513175 | 0.74 | KMT2A (1.00) | LGALS8LGALS3KMT2AFLT3KDM4E | |
| SCHEMBL31287808 | 0.74 | KDM4E (0.56) | KMT2AFLT3KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852135-A | N-acyl sulfonamide compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-10-29 | — | — | CN | disclosed |