Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287946 | 1.00 | MAP4K1 (0.40) | MAP4K1TYK2HDAC1HCAR3MEN1 | |
| SCHEMBL29666324 | 0.83 | NPC1 (0.52) | TYK2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29829392 | 0.83 | NPC1 (0.52) | TYK2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL32677813 | 0.81 | TYK2 (0.43) | TYK2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30636222 | 0.81 | NNMT (0.51) | MAP4K1HCAR3ALDH1A1 | |
| SCHEMBL31280829 | 0.80 | LRRK2 (0.41) | MAP4K1TYK2JAK1 | |
| SCHEMBL31017468 | 0.79 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL31017485 | 0.79 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL31017395 | 0.79 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL32677838 | 0.77 | HCAR3 (0.49) | HDAC1HCAR3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254834-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |