Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 7/20 | 0.42 |
| ▸ | FLT4 | P35916 | 7/20 | 0.42 |
| ▸ | KDR | P35968 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31288176 | 0.81 | PTPN1 (0.51) | CA12CA2CA9PTPN1MAPT | |
| SCHEMBL31288141 | 0.81 | PTPN1 (0.48) | CA12CA2CA9PTPN1MAPT | |
| SCHEMBL12325012 | 0.75 | HSD17B1 (0.59) | MAPTHSD17B1 | |
| SCHEMBL31288142 | 0.74 | CYP3A4 (0.48) | HSD17B1 | |
| SCHEMBL31288126 | 0.72 | PTPN1 (0.55) | PTPN1MAPTMAPK1NPSR1 | |
| SCHEMBL5184574 | 0.71 | VCP (0.55) | MAPTFLT1FLT4KDRDYRK1A | |
| SCHEMBL4098150 | 0.70 | CYP1A2 (0.48) | MAPTPOLBHSD17B1 | |
| SCHEMBL31288154 | 0.70 | CA12 (0.47) | CA12CA2CA9MAPTCA1 | |
| SCHEMBL31288144 | 0.70 | PTPN1 (0.53) | PTPN1MAPT | |
| SCHEMBL31288170 | 0.70 | HDAC6 (0.45) | CA2PTPN1CA1L3MBTL1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024258591-A2 | NOVEL INHIBITORS OF HISTONE DEMETHYLASES AND COMPOSITIONS AND METHODS THEREOF | XIANG YIBIN (US) | 2024-12-19 | — | — | WO | disclosed |