Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | BRAF | P15056 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747761 | 0.83 | EPHX2 (0.73) | EPHX2SMN1; SMN2CNR1BRAFMAPK14 | |
| SCHEMBL4974321 | 0.82 | EPHX2 (0.70) | EPHX2SMN1; SMN2BRAFMAPK14KDR | |
| SCHEMBL11926736 | 0.81 | KDM4E (0.65) | EPHX2SMN1; SMN2BRAFMAPK14KDR | |
| SCHEMBL10132797 | 0.80 | EPHX2 (0.67) | EPHX2BRAFMAPK14LMNAMAPT | |
| SCHEMBL4264251 | 0.79 | EPHX2 (1.00) | EPHX2SMN1; SMN2CNR1BRAFMAPK14 | |
| SCHEMBL4256144 | 0.78 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL4269280 | 0.77 | EPHX2 (0.86) | EPHX2 | |
| SCHEMBL22834260 | 0.77 | SMN1; SMN2 (1.00) | EPHX2SMN1; SMN2CNR1LMNAMAPT | |
| SCHEMBL18921088 | 0.77 | EPHX2 (0.62) | EPHX2SMN1; SMN2BRAFMAPK14LMNA | |
| SCHEMBL6692679 | 0.76 | CA12 (0.58) | EPHX2MAPTGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161306-A | Bicycloacetamide structural compound, preparation method and pharmaceutical application thereof | 河南大学 | 2024-12-20 | — | — | CN | disclosed |