Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697390 | 0.97 | CA12 (0.56) | CA12CA1CA2CA9CA4 | |
| SCHEMBL6689381 | 0.96 | FAAH (0.56) | CA12CA1CA2CA9CA4 | |
| SCHEMBL6696313 | 0.88 | MAPT (0.63) | MAPTKMT2AMEN1POLBHPGD | |
| SCHEMBL14593657 | 0.86 | EPHX1 (0.67) | KMT2AFAAHHTTEPHX1EPHX2 | |
| SCHEMBL5386322 | 0.86 | EPHX1 (0.67) | KMT2AFAAHHTTEPHX1EPHX2 | |
| SCHEMBL14593705 | 0.86 | EPHX1 (0.67) | KMT2AFAAHHTTEPHX1EPHX2 | |
| SCHEMBL14593707 | 0.86 | EPHX1 (0.67) | CA12CA1CA2CA9CA4 | |
| SCHEMBL27710648 | 0.85 | CA12 (0.63) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3146895 | 0.82 | FPR2 (0.66) | CA12CA1CA2CA9CA4 | |
| SCHEMBL7288606 | 0.82 | GAA (0.63) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |