Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28283593 | 0.96 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| Hydrogen Peroxide SCHEMBL15610564 | 0.92 | — | — | |
| Hydrogen Peroxide SCHEMBL28219767 | 0.92 | TSHR (0.91) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| Acetic Acid SCHEMBL31567845 | 0.88 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| Acetic Acid SCHEMBL7524409 | 0.88 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| Acetic Acid SCHEMBL28388644 | 0.88 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| Acetic Acid SCHEMBL2495577 | 0.88 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| Acetic Acid SCHEMBL396817 | 0.88 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HSD17B10FFAR3 | |
| SCHEMBL523 | 0.88 | — | — | |
| SCHEMBL1331977 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642361-B2 | Thiophene and furan compounds | ELI LILLY AND COMPANY (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070105852-A1 | Thiophene and furan compounds | ELI LILLY AND COMPANY | 2007-05-10 | — | — | US | disclosed |
| US-20060287527-A1 | Process for producing acrylic acid derivative | NIPPON SODA CO., LTD. (JP) | 2006-12-21 | — | — | US | disclosed |
| EP-1706395-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005070916-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |
| US-20040152894-A1 | Process for producing acrylic acid derivative | NIPPON SODA CO. LTD (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1142857-A1 | PROCESSES FOR PRODUCING ACRYLIC ACID DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-4208479-A | HIGHLY SENSITIVE QUALITATIVE AND QUANTITATIVE ANALYSIS | SYVA COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152894-A1 | Process for producing acrylic acid derivative | OXGR1, GART, HAO2 | ALDH1A1 117/4885TSHR 1302/4885TDP1 3275/4885 |
| US-20070105852-A1 | Thiophene and furan compounds | PSEN2, PSEN1, TPMT | ALDH1A1 1344/4885TSHR 980/4885TDP1 287/4885 |
| US-20060287527-A1 | Process for producing acrylic acid derivative | APEH, HAAO, ASNS | ALDH1A1 214/4885TSHR 1928/4885TDP1 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.