Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30164323 | 0.92 | EPHX2 (0.57) | ALDH1A1SMN1; SMN2EPHX2PTPN1HPGD | |
| SCHEMBL4032240 | 0.86 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2EPHX2HPGDMTNR1A | |
| SCHEMBL11399325 | 0.83 | EPHX2 (0.71) | ALDH1A1SMN1; SMN2EPHX2HPGDRXFP1 | |
| SCHEMBL13745650 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2EPHX2TSHRNPC1 | |
| SCHEMBL11403472 | 0.77 | HPGD (0.78) | ALDH1A1SMN1; SMN2EPHX2HPGDTSHR | |
| SCHEMBL13746152 | 0.76 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2EPHX2TSHRPKM | |
| SCHEMBL16102804 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2EPHX2HPGDRXFP1 | |
| SCHEMBL18415442 | 0.76 | PTPN1 (0.63) | ALDH1A1SMN1; SMN2PTPN1HPGDPKM | |
| SCHEMBL3173347 | 0.75 | RXFP1 (0.55) | ALDH1A1SMN1; SMN2EPHX2HPGDRXFP1 | |
| SCHEMBL14031174 | 0.75 | PTPN1 (0.61) | SMN1; SMN2PTPN1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4461715-A1 | METHOD FOR REMOVING TERT-BUTOXYCARBONYL GROUPS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-11-13 | — | — | EP | disclosed |