SCHEMBL31291173

SCHEMBL31291173

CCCCCCCCCCCCSSc1ccccn1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.52
EHMT1 Q9H9B1 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
HDAC1 Q13547 13/20 0.42
HDAC2 Q92769 10/20 0.42
HDAC4 P56524 3/20 0.42
HDAC6 Q9UBN7 2/20 0.42
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
USP2 O75604 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580067 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL27398355 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL1039828 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL19104359 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL3487114 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL23963850 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL10077568 1.00 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL463670 0.98 EHMT2 (0.53) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL12107793 0.93 EHMT2 (0.55) EHMT2EHMT1APOBEC3GHDAC1HDAC2
SCHEMBL30195173 0.93 EHMT2 (0.55) EHMT2EHMT1APOBEC3GHDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720284-A2 NOVEL SCN10A RNAI AGENTS AND USES THEREOF Eli Lilly and Company (US) 2026-04-08 EP disclosed
WO-2024249240-A2 NOVEL SCN10A RNAI AGENTS AND USES THEREOF ELI LILLY AND COMPANY (US) 2024-12-05 WO disclosed