Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993190 | 1.00 | DGAT1 (0.41) | DGAT1ALDH1A1L3MBTL1PTGDR2SMN1; SMN2 | |
| SCHEMBL4504501 | 0.87 | PTGDR2 (0.43) | DGAT1ALDH1A1L3MBTL1PTGDR2SMN1; SMN2 | |
| SCHEMBL18512324 | 0.86 | AAK1 (0.43) | DGAT1ALDH1A1L3MBTL1PTGDR2SMN1; SMN2 | |
| SCHEMBL18340197 | 0.81 | HPGD (0.41) | ALDH1A1PTGDR2SMN1; SMN2LMNAKMT2A | |
| SCHEMBL22918231 | 0.81 | PTGDR2 (0.43) | ALDH1A1L3MBTL1PTGDR2SMN1; SMN2LMNA | |
| SCHEMBL29835966 | 0.81 | PTGDR2 (0.43) | ALDH1A1L3MBTL1PTGDR2SMN1; SMN2LMNA | |
| SCHEMBL1627738 | 0.81 | HDAC3 (0.46) | ALDH1A1SMN1; SMN2LMNAKMT2APLCG1 | |
| SCHEMBL31251995 | 0.80 | PTGDR2 (0.45) | ALDH1A1L3MBTL1PTGDR2SMN1; SMN2LMNA | |
| SCHEMBL2243013 | 0.79 | ALDH1A1 (0.40) | DGAT1ALDH1A1L3MBTL1PTGDR2SMN1; SMN2 | |
| SCHEMBL31292275 | 0.79 | HTT (0.53) | LMNAKMT2ANOTUMPLCG1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024521-A1 | SUBSTITUTED PIPERIDINEDIONES FOR TARGETED PROTEIN DEGRADATION | MONTE ROSA THERAPEUTICS, INC. (US) | 2025-01-30 | — | — | WO | disclosed |