SCHEMBL312923

SCHEMBL312923

O=P(Cl)(OCC(Cl)(Cl)Cl)OCC(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25437665 0.97 TP53 (0.32) TP53TDP1
SCHEMBL6902693 0.82 TP53 (0.46) TP53TDP1
SCHEMBL9818290 0.79 MAPK1 (0.33)
SCHEMBL5983546 0.79 ALDH1A1 (0.41)
SCHEMBL4995915 0.78 KDM4E (0.31) TP53TDP1
SCHEMBL10567120 0.77
SCHEMBL2782186 0.77 TP53 (0.39) TP53TDP1
SCHEMBL8927345 0.76
SCHEMBL9818237 0.74 SMN1; SMN2 (0.40) TP53TDP1
SCHEMBL20543192 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006012425-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2006-02-02 WO claimed
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION, A CORPORATION OF THE STATE OF DELAWARE (US) 2005-05-19 US claimed
EP-1521762-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2005-04-13 EP claimed
US-20040267007-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor CORIXA CORPORATION 2004-12-30 US claimed
US-20040138182-A1 Colchicine derivatives, process for preparing them, products obtained therefrom and use thereof AVENTIS PHARMA S.A. (FR) 2004-07-15 US claimed
WO-2004005308-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2004-01-15 WO claimed
US-4229203-A INCREASED SUCROSE YIELD W. R. GRACE & CO. (US) 1980-10-21 US claimed
EP-4744667-A2 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF The Queen's University Of Belfast (GB) 2026-05-20 EP disclosed
US-12594292-B2 Antiviral prodrugs, intermediate-and long-acting formulations and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-07 US disclosed
WO-2025151707-A1 METHOD FOR PREPARING MULTIMERS OF PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS ENTRADA THERAPEUTICS, INC. (US) 2025-07-17 WO disclosed
US-20250177428-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-06-05 US disclosed
US-20250163093-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2025-05-22 US disclosed
CN-110662542-B Nicotinoyl nucleosides and reduced nicotinoyl nucleosides, modified derivatives thereof, phosphorylated analogs thereof, adenosine dinucleotide conjugates thereof, and efficient and scalable synthesis of novel crystalline forms thereof 英国贝尔法斯特女王大学 2025-04-08 CN disclosed
EP-0272330-A1 1,1,2-TRIARYL-1-BUTENE DERIVATIVES TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1988-06-29 EP disclosed
US-4670424-A Cyclic pyrophosphates of purine and pyrimidine acyclonucleosides MERCK & CO., INC. (US) 1987-06-02 US disclosed
EP-0138656-A1 Cyclic pyrophosphates of purine and pyrimidine acyclonucleosides, their preparation and their application in anti-viral compositions MERCK & CO. INC. (US) 1985-04-24 EP disclosed
US-4469682-A PARASITICIDES MERCK & CO., INC. (US) 1984-09-04 US disclosed
EP-0115930-A1 Avermectin and milbemycin phosphate esters MERCK & CO. INC. (US) 1984-08-15 EP disclosed
US-4229203-A INCREASED SUCROSE YIELD W. R. GRACE & CO. (US) 1980-10-21 US disclosed
US-4145540-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163093-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF NAPRT, NAMPT, CD38 TP53 3698/4885TDP1 629/4885
US-12594292-B2 Antiviral prodrugs, intermediate-and long-acting formulations and methods ACE2, SARS1, FURIN TP53 3086/4885TDP1 2997/4885
US-20040267007-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor DDOST, STT3A, STT3B TP53 3230/4885TDP1 4410/4885
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor DDOST, AGL, GALE TP53 2990/4885TDP1 4340/4885
US-20040138182-A1 Colchicine derivatives, process for preparing them, products obtained therefrom and use thereof WEE1, NOTUM, WEE2 TP53 158/4885TDP1 98/4885
US-20250177428-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS SARS1, ACE2, FURIN TP53 2583/4885TDP1 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.