Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21178229 | 0.89 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SMYD3CPN1 | |
| SCHEMBL31292910 | 0.84 | SCN1A (0.45) | MEN1KMT2ACYP2D6POLBMAPT | |
| SCHEMBL31293221 | 0.79 | MAPT (0.48) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL17729118 | 0.78 | CPN1 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6SMYD3 | |
| SCHEMBL31293254 | 0.77 | GPR119 (0.53) | MEN1KMT2ATP53 | |
| SCHEMBL5189078 | 0.75 | DPP4 (0.54) | SLC6A2SLC6A4SLC6A3SMYD3 | |
| SCHEMBL5717304 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6SMYD3 | |
| SCHEMBL31381427 | 0.75 | CPN1 (0.45) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL28763756 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6SMYD3 | |
| SCHEMBL27697385 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747236-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024210-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |