Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NMT1 | P30419 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293123 | 0.87 | SLC6A2 (0.50) | NMT1SLC6A2SLC6A4HTR2CTAAR1 | |
| SCHEMBL21178229 | 0.84 | SLC6A2 (0.47) | MAPTSLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL31293186 | 0.80 | MEN1 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31292855 | 0.79 | SLC6A2 (0.47) | MAPTALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2672357 | 0.76 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL2425450 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL17281 | 0.74 | TAAR1 (0.60) | MAPTALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL17280 | 0.74 | TAAR1 (0.60) | MAPTALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL31506228 | 0.74 | TAAR1 (0.60) | MAPTALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL13476450 | 0.73 | MEN1 (0.49) | ALDH1A1SLC6A2SLC6A4SLC6A3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747236-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024210-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |