Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904781 | 0.82 | L3MBTL1 (0.54) | GRIN2BL3MBTL1ATMDRD4KDM4E | |
| SCHEMBL4638141 | 0.82 | L3MBTL1 (0.54) | GRIN2BL3MBTL1ATMDRD4KDM4E | |
| SCHEMBL4638143 | 0.82 | L3MBTL1 (0.54) | GRIN2BL3MBTL1ATMDRD4KDM4E | |
| SCHEMBL25062425 | 0.78 | GRIN2B (0.47) | GRIN2BL3MBTL1ATMDRD4DRD2 | |
| SCHEMBL7366530 | 0.77 | DRD4 (0.57) | DRD4DRD2DRD3 | |
| SCHEMBL2902494 | 0.76 | DRD4 (0.52) | GRIN2BDRD4KDM4EDRD2DRD3 | |
| SCHEMBL1759419 | 0.76 | DRD4 (0.55) | GRIN2BDRD4DRD2DRD3 | |
| SCHEMBL3521678 | 0.75 | DRD4 (0.57) | HPGDGRIN2BDRD4KDM4EDRD2 | |
| SCHEMBL159384 | 0.75 | DRD4 (0.57) | HPGDGRIN2BDRD4KDM4EDRD2 | |
| SCHEMBL3519935 | 0.75 | DRD4 (0.57) | HPGDGRIN2BDRD4KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747236-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024210-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |