SCHEMBL159384

SCHEMBL159384

O=C(O)C1CN(Cc2ccccc2)CCO1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 10/20 0.57
DRD2 P14416 2/20 0.53
DRD3 P35462 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
GRIN2B Q13224 2/20 0.51
S1PR5 Q9H228 2/20 0.50
S1PR1 P21453 1/20 0.50
CNR2 P34972 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.48
AGTR2 P50052 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3521678 1.00 DRD4 (0.57) DRD4DRD2DRD3CYP1A2CYP3A4
SCHEMBL3519935 1.00 DRD4 (0.57) DRD4DRD2DRD3CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL12610726 0.98 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL12610644 0.98 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL917642 0.98 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4
SCHEMBL4836218 0.98 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4
SCHEMBL27641050 0.91 DRD4 (0.57) DRD4DRD2DRD3CYP1A2CYP3A4
SCHEMBL4129378 0.90 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4
SCHEMBL12696566 0.90 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4
SCHEMBL2447401 0.90 DRD4 (0.56) DRD4DRD2DRD3CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
US-7109243-B2 Inhibitors of cathepsin S IRM LLC (BM) 2006-09-19 US claimed
US-12630556-B2 Substituted [1,2,4]triazolo[1,5-a]pyrimidin-7-yl compounds as PDE2 inhibitors DART NEUROSCIENCE LLC (US) 2026-05-19 US disclosed
US-12552796-B2 EED inhibitor, and preparation method therefor and use thereof JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) 2026-02-17 US disclosed
EP-3980401-B1 PURINE DERIVATIVES, AS NR2B NEGATIVE MODULATORS AND THE USE THEREOF AS MEDICAMENT, IN PARTICULAR FOR TREATING DEPRESSIVE DISORDERS BOEHRINGER INGELHEIM INT (DE) 2026-01-28 EP disclosed
US-12522618-B2 Copper complexes for treatment of neurodegenerative disorders ALS THERAPY DEVELOPMENT INSTITUTE (US) 2026-01-13 US disclosed
EP-4056570-B1 EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF UNIV SHANGHAI TECHNOLOGY (CN) 2026-01-07 EP disclosed
EP-4626865-A1 CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS Protego Biopharma, Inc. (US) 2025-10-08 EP disclosed
US-20250092047-A1 SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS DART NEUROSCIENCE LLC 2025-03-20 US disclosed
US-20240368195-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS ALS THERAPY DEVELOPMENT INST (US) 2024-11-07 US disclosed
US-20240309003-A1 HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE VIGIL NEUROSCIENCE, INC. (US) 2024-09-19 US disclosed
CN-1889940-A Treatment of personality changes due to hot flashes, impulse control disorders and systemic medical conditions LILLY CO ELI (US) 2007-01-03 CN disclosed
CN-1878762-A Morpholine derivatives as norepinephrine reuptake inhibitors LILLY CO ELI (US) 2006-12-13 CN disclosed
US-7109243-B2 Inhibitors of cathepsin S IRM LLC (BM) 2006-09-19 US disclosed
US-20050222139-A1 Non-peptide gnrh antagonists FERRING B.V. (NL) 2005-10-06 US disclosed
CN-1662498-A Novel tetrahydropyridine derivatives as renin inhibitors ACTELION PHARMACEUTICALS LTD (CH) 2005-08-31 CN disclosed
EP-1485356-A1 NON-PEPTIDE GnRH ANTAGONISTS Ferring BV (NL) 2004-12-15 EP disclosed
WO-2004084842-A2 INHIBITORS OF CATHEPSIN S IRM LLC (BM) 2004-10-07 WO disclosed
US-20040198780-A1 Inhibitors of cathepsin S IRM LLC (BM) 2004-10-07 US disclosed
WO-2003078398-A1 NON-PEPTIDE GnRH ANTAGONISTS FERRING BV (NL) 2003-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222139-A1 Non-peptide gnrh antagonists GNRHR, BRS3, FSHR DRD4 248/4885DRD2 261/4885DRD3 121/4885
US-20250092047-A1 SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS PDE12, PDE2A, TDP2 DRD4 1166/4885DRD2 662/4885DRD3 1370/4885
US-20240309003-A1 HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE MSR1, FPR2, CD14 DRD4 2732/4885DRD2 1052/4885DRD3 2484/4885
US-12552796-B2 EED inhibitor, and preparation method therefor and use thereof HSD11B1, CYP4A11, CYP8B1 DRD4 2050/4885DRD2 797/4885DRD3 871/4885
US-20040198780-A1 Inhibitors of cathepsin S CTSS, CTSK, CTSE DRD4 4490/4885DRD2 4032/4885DRD3 3449/4885
US-20240368195-A1 COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS SOD1, SMN1; SMN2, CLN6 DRD4 3963/4885DRD2 4129/4885DRD3 4085/4885
US-12630556-B2 Substituted [1,2,4]triazolo[1,5-a]pyrimidin-7-yl compounds as PDE2 inhibitors PDE1A, PDE12, PDE1B DRD4 389/4885DRD2 210/4885DRD3 722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.