Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR known ✓ | Q92847 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.65 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875979 | 0.98 | SLC15A2 (0.67) | SLC15A2SLC6A5FAAHCNR1CNR2 | |
| SCHEMBL26006164 | 0.91 | SLC15A2 (0.70) | SLC15A2SLC6A5FAAHCNR1CNR2 | |
| Acetic Acid SCHEMBL29453855 | 0.85 | SLC15A2 (0.59) | SLC15A2SLC6A5FAAHCNR1CNR2 | |
| SCHEMBL22314402 | 0.84 | SLC15A2 (0.69) | SLC15A2SLC6A5FAAHCNR1CNR2 | |
| Acetic Acid SCHEMBL31696243 | 0.83 | SLC15A2 (0.94) | SLC15A2SLC6A5CPB2RENEPHX2 | |
| Acetic Acid SCHEMBL29360257 | 0.82 | SLC15A2 (0.92) | SLC15A2SLC6A5CPB2RENEPHX2 | |
| SCHEMBL16731429 | 0.81 | SLC15A2 (0.76) | SLC15A2SLC6A5CPB2RENEPHX2 | |
| SCHEMBL30175135 | 0.80 | SLC15A2 (1.00) | SLC15A2SLC6A5CPB2RENEPHX2 | |
| SCHEMBL22462015 | 0.80 | SLC15A2 (1.00) | SLC15A2SLC6A5CPB2RENEPHX2 | |
| SCHEMBL19087235 | 0.80 | SLC15A2 (1.00) | SLC15A2SLC6A5CPB2RENEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4464307-A1 | COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME | MPLUS COSMETICS S.R.L. (IT) | 2024-11-20 | — | — | EP | disclosed |
| US-20240374498-A1 | COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME | MPLUS COSMETICS S.R.L. (IT) | 2024-11-14 | — | — | US | disclosed |