SCHEMBL22314402

SCHEMBL22314402

CCCCCCCCCCCCCCCCCC(=O)NC(CS)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.69
▸ SLC6A5 Q9Y345 2/20 0.61
▸ FAAH O00519 2/20 0.47
▸ CNR1 P21554 2/20 0.47
▸ CNR2 P34972 2/20 0.47
▸ ITGB3 P05106 1/20 0.44
▸ ITGA2B P08514 1/20 0.44
▸ NOD1 Q9Y239 3/20 0.43
▸ CPB2 Q96IY4 2/20 0.43
▸ EPHX2 P34913 1/20 0.42
▸ REN P00797 2/20 0.42
▸ TLR2 O60603 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26006164 0.89 SLC15A2 (0.70) SLC15A2SLC6A5FAAHCNR1CNR2
SCHEMBL15134134 0.89 SLC15A2 (0.54) SLC15A2SLC6A5FAAHCNR1CNR2
SCHEMBL15134133 0.86 SLC15A2 (0.51) SLC15A2SLC6A5FAAHCNR1CNR2
SCHEMBL29875979 0.85 SLC15A2 (0.67) SLC15A2SLC6A5FAAHCNR1CNR2
SCHEMBL30562710 0.84 SLC6A5 (0.69) SLC6A5ITGB3ITGA2BNOD1TLR2
SCHEMBL29941997 0.84 SLC6A5 (0.69) SLC6A5ITGB3ITGA2BNOD1TLR2
Acetic Acid SCHEMBL31293492 0.84 SLC15A2 (0.65) SLC15A2SLC6A5FAAHCNR1CNR2
SCHEMBL29942005 0.83 SLC6A5 (0.51) SLC15A2SLC6A5ITGB3ITGA2BNOD1
Acetic Acid SCHEMBL29453855 0.83 SLC15A2 (0.59) SLC15A2SLC6A5FAAHCNR1CNR2
SCHEMBL22462015 0.82 SLC15A2 (1.00) SLC15A2SLC6A5CPB2EPHX2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446393-B2 Non-viral gene delivery agent comprising lipopeptide (LP) compounds MONASH UNIVERSITY (AU) 2022-09-20 — — US disclosed
US-20200246487-A1 NON-VIRAL GENE DELIVERY AGENT COMPRISING LIPOPEPTIDE (LP) COMPOUNDS MONASH UNIVERSITY (AU) 2020-08-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11446393-B2 Non-viral gene delivery agent comprising lipopeptide (LP) compounds LNPEP, TLR9, LPXN SLC15A2 1825/4885SLC6A5 4189/4885FAAH 2645/4885
US-20200246487-A1 NON-VIRAL GENE DELIVERY AGENT COMPRISING LIPOPEPTIDE (LP) COMPOUNDS LNPEP, TLR9, LPXN SLC15A2 1825/4885SLC6A5 4189/4885FAAH 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback