SCHEMBL31294024

SCHEMBL31294024

CN(C(=O)Nc1cccc(C(F)(F)F)c1)C1CC2(CNC2)C1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.66
POLB P06746 1/20 0.66
TP53 P04637 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.53
EPHX2 P34913 2/20 0.51
LMNA P02545 1/20 0.51
CXCR3 P49682 1/20 0.49
DCUN1D1 Q96GG9 2/20 0.49
GRM5 P41594 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
RXFP1 Q9HBX9 1/20 0.47
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
UBE2M P61081 1/20 0.45
GAA P10253 1/20 0.45
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293563 0.84 DCUN1D1 (0.54) RAB9APOLBTP53SMN1; SMN2EPHX2
SCHEMBL31293960 0.79 EPHX2 (0.65) RAB9ASMN1; SMN2EPHX2DCUN1D1GRM5
SCHEMBL31294047 0.79 SMN1; SMN2 (0.55) RAB9ASMN1; SMN2EPHX2LMNAMEN1
Fluometuron SCHEMBL1701226 0.76 TP53 (1.00) RAB9APOLBTP53SMN1; SMN2LMNA
Fluometuron SCHEMBL67252 0.76 TP53 (1.00) RAB9APOLBTP53SMN1; SMN2LMNA
Fluometuron SCHEMBL29598187 0.76 TP53 (1.00) RAB9APOLBTP53SMN1; SMN2LMNA
SCHEMBL14561889 0.75 TP53 (0.80) RAB9APOLBTP53SMN1; SMN2LMNA
Fluometuron SCHEMBL28422185 0.75 TP53 (0.97) RAB9APOLBTP53SMN1; SMN2LMNA
Trifluoroacetic Acid SCHEMBL20983814 0.74 SMN1; SMN2 (0.49) RAB9ASMN1; SMN2EPHX2LMNADCUN1D1
SCHEMBL23169509 0.74 TP53 (0.74) RAB9APOLBTP53SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP disclosed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO disclosed