Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23060409 | 0.82 | MEN1 (0.65) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL31293960 | 0.81 | EPHX2 (0.65) | SMN1; SMN2MEN1KMT2AMAPTXBP1 | |
| SCHEMBL31294024 | 0.79 | RAB9A (0.66) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL13568442 | 0.79 | MAPT (0.58) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL31293563 | 0.79 | DCUN1D1 (0.54) | SMN1; SMN2EPHX2RAB9ALMNA | |
| SCHEMBL31293526 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| Trifluoroacetic Acid SCHEMBL20983814 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AMAPTEPHX2 | |
| SCHEMBL5142590 | 0.76 | MAPT (0.77) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL31236338 | 0.76 | MAPT (0.77) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL5805724 | 0.75 | MAPT (0.70) | SMN1; SMN2MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |