SCHEMBL31293563

SCHEMBL31293563

O=C(Nc1cccc(C(F)(F)F)c1)N(CC(F)(F)F)C1CC2(CNC2)C1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 12/20 0.54
TP53 P04637 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
UBE2M P61081 10/20 0.49
EPHX2 P34913 1/20 0.48
POLB P06746 1/20 0.48
RAB9A P51151 1/20 0.48
CXCR3 P49682 1/20 0.46
LMNA P02545 1/20 0.46
GRM5 P41594 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31294024 0.84 RAB9A (0.66) DCUN1D1TP53SMN1; SMN2UBE2MEPHX2
SCHEMBL31293771 0.80 DCUN1D1 (0.47) DCUN1D1TP53UBE2MPOLBRAB9A
SCHEMBL31294047 0.79 SMN1; SMN2 (0.55) SMN1; SMN2EPHX2RAB9ALMNA
SCHEMBL31293960 0.77 EPHX2 (0.65) DCUN1D1SMN1; SMN2UBE2MEPHX2RAB9A
SCHEMBL31293791 0.73 DCUN1D1 (0.42) DCUN1D1UBE2MCXCR3
Trifluoroacetic Acid SCHEMBL20983814 0.72 SMN1; SMN2 (0.49) DCUN1D1SMN1; SMN2EPHX2RAB9ALMNA
SCHEMBL18640267 0.70 DCUN1D1 (1.00) DCUN1D1UBE2M
Fluometuron SCHEMBL29598187 0.68 TP53 (1.00) TP53SMN1; SMN2POLBRAB9ALMNA
Fluometuron SCHEMBL67252 0.68 TP53 (1.00) TP53SMN1; SMN2POLBRAB9ALMNA
Fluometuron SCHEMBL1701226 0.68 TP53 (1.00) TP53SMN1; SMN2POLBRAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP disclosed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO disclosed