Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | POR | P16435 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83136 | 0.84 | ADORA2A (0.53) | ELANEMAOAMAOBMAPTMAPK1 | |
| SCHEMBL10883505 | 0.82 | MAOA (0.48) | ELANEMAOAMAOBMAPTMAPK1 | |
| SCHEMBL6761959 | 0.81 | ELANE (0.69) | ELANEMAOAMAOBPOLBNQO1 | |
| Anthracene SCHEMBL28422390 | 0.80 | L3MBTL1 (0.47) | ELANEMAOAMAPTMAPK1ALDH1A1 | |
| SCHEMBL29405931 | 0.79 | ELANE (0.69) | ELANEMAOAMAOBPOLBLCK | |
| SCHEMBL14174532 | 0.79 | ADORA2A (0.68) | ELANEMAOAMAOBPOLBLCK | |
| SCHEMBL30610015 | 0.79 | ELANE (0.65) | ELANEMAOAMAOBPOLBLCK | |
| SCHEMBL30610009 | 0.79 | ELANE (0.69) | ELANEMAOAMAOBPOLBLCK | |
| SCHEMBL29435136 | 0.79 | ELANE (0.69) | ELANEMAOAMAOBPOLBLCK | |
| SCHEMBL30610034 | 0.79 | ADORA2A (0.68) | ELANEMAOAMAOBPOLBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118806746-A | Application of 1, 8-dihydroxy-3-succinic acid monoethyl ester-6-methylanthraquinone in preparation of anti-liver cancer drugs | 哈尔滨医科大学 | 2024-10-22 | — | — | CN | claimed |
| CN-118806746-A | Application of 1, 8-dihydroxy-3-succinic acid monoethyl ester-6-methylanthraquinone in preparation of anti-liver cancer drugs | 哈尔滨医科大学 | 2024-10-22 | — | — | CN | disclosed |