Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247305 | 0.83 | LMNA (0.41) | KDM4EKMT2ALMNAMAPTMEN1 | |
| SCHEMBL13521684 | 0.82 | KMO (0.46) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL13521571 | 0.79 | USP2 (0.42) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL13521704 | 0.78 | MEN1 (0.37) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL13521716 | 0.77 | MEN1 (0.40) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL13521594 | 0.77 | MEN1 (0.48) | KMT2AMEN1ALDH1A1TP53POLB | |
| SCHEMBL13521727 | 0.76 | MEN1 (0.39) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL13521726 | 0.74 | MEN1 (0.52) | KMT2AMAPTMEN1NPSR1TP53 | |
| SCHEMBL13521729 | 0.74 | MEN1 (0.39) | KMT2AMEN1NPSR1TP53POLB | |
| SCHEMBL3246664 | 0.73 | MEN1 (0.41) | KMT2AMAPTMEN1NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |