Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121499 | 0.82 | KLKB1 (0.37) | NR4A2TP53RAB9AKLF5SMN1; SMN2 | |
| SCHEMBL14206713 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNAHDAC6 | |
| SCHEMBL344751 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAHDAC6BMP1FBP1 | |
| SCHEMBL15001323 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAHDAC6BMP1FBP1 | |
| SCHEMBL13447332 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RAB9ALMNABMP1 | |
| SCHEMBL2682118 | 0.79 | FPR2 (0.45) | ALDH1A1NR4A2BMP1CES1 | |
| SCHEMBL13412497 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TP53RAB9AKLF5SMN1; SMN2 | |
| SCHEMBL27207772 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNABMP1 | |
| SCHEMBL15145304 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAHDAC6BMP1FBP1 | |
| SCHEMBL1980837 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAHDAC6BMP1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |