Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | EDNRA | P25101 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.59 |
| ▸ | PPIA | P62937 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351351 | 0.86 | MEN1 (0.71) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL3130823 | 0.85 | ALDH1A1 (0.67) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL3278437 | 0.83 | ALDH1A1 (0.69) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL9230514 | 0.82 | PKM (0.90) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL3127889 | 0.80 | SCN9A (0.57) | MEN1KMT2APKMALDH1A1SCN3A | |
| SCHEMBL3127241 | 0.80 | MEN1 (0.60) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL14408123 | 0.80 | SCN3A (0.61) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL15116291 | 0.80 | PTPN1 (0.82) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL8388562 | 0.80 | PPIA (0.76) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL1650814 | 0.80 | ALDH1A1 (0.72) | MEN1KMT2APKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |