Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6019337 | 0.87 | NR1H2 (0.43) | NR1H2ASGR1SPRNFKB1NFKB2 | |
| SCHEMBL6019334 | 0.87 | NR1H2 (0.43) | NR1H2ASGR1SPRNFKB1NFKB2 | |
| SCHEMBL15017085 | 0.82 | CNR2 (0.38) | NR1H2ASGR1SPRNFKB1NFKB2 | |
| SCHEMBL24438464 | 0.79 | ALOX5 (0.39) | ASGR1SPRNFKB1NFKB2RELA | |
| SCHEMBL803364 | 0.79 | USP30 (0.36) | NR1H2SPRHTR2CSLC6A4 | |
| SCHEMBL13627183 | 0.78 | SPR (0.34) | NR1H2ASGR1SPRNFKB1NFKB2 | |
| SCHEMBL21574018 | 0.78 | HTR2C (0.42) | HTR2CSLC6A4 | |
| SCHEMBL24622293 | 0.78 | NR1H2 (0.47) | NR1H2ASGR1NFKB1NFKB2RELA | |
| SCHEMBL8911411 | 0.78 | HTR2C (0.42) | HTR2CSLC6A4 | |
| SCHEMBL25048008 | 0.78 | NR1H2 (0.38) | NR1H2ASGR1SPRNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024245310-A1 | THIAZOLYL OR THIADIAZOLYL AMIDES DERIVATIVES AND USE THEREOF | NINGBO NEWBAY TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-12-05 | — | — | WO | disclosed |