SCHEMBL31295129

SCHEMBL31295129

COC(=O)C1CCN=C(OC)C1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.39
TP53 P04637 1/20 0.35
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
PKM P14618 1/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530825 0.84 CYP1A2 (0.38)
SCHEMBL2153336 0.83 PDK1 (0.42) KDM4EKMT2AMEN1
SCHEMBL9373486 0.79 NOS3 (0.46) BRD4TP53CHRNB2CHRNA4CHRNB4
Hydrochloric Acid SCHEMBL8308967 0.77 NOS3 (0.44) BRD4TP53
SCHEMBL2153141 0.76 BRD4 (0.40) BRD4TP53CHRNB2CHRNA4CHRNB4
SCHEMBL1712752 0.70 TP53 (0.47) BRD4TP53CHRNB2CHRNA4CHRNB4
SCHEMBL7627716 0.68 NOS3 (0.55)
SCHEMBL2415202 0.67
SCHEMBL907587 0.67 PPM1B (0.34) BRD4TP53KDM4ESMN1; SMN2
SCHEMBL244740 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119698412-A 5-HT2A receptor agonist, and preparation method and application thereof 上海翊石医药科技有限公司 2025-03-25 CN disclosed
WO-2025021120-A1 5-HT2A RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2025-01-30 WO disclosed