Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490265 | 0.80 | MGLL (0.48) | MGLLMAPK1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10059343 | 0.79 | HSD17B10 (0.60) | MGLLALOX5HPGDMAPTSMN1; SMN2 | |
| SCHEMBL6536599 | 0.77 | CYP1A2 (0.53) | MGLLHPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL21257468 | 0.77 | CRBN (0.59) | MGLLALOX5SOD1HPGDMAPT | |
| SCHEMBL6535778 | 0.77 | HSP90AA1 (0.52) | MGLLALOX5HPGDMAPTALDH1A1 | |
| SCHEMBL327268 | 0.76 | MGLL (0.55) | MGLLALOX5MAPK1HPGDMAPT | |
| SCHEMBL13932944 | 0.75 | POLB (0.50) | MGLLMAPK1HPGDMAPTLMNA | |
| SCHEMBL2222230 | 0.74 | MGLL (0.50) | MGLLALDH1A1 | |
| SCHEMBL18050078 | 0.74 | MGLL (0.54) | MGLLHPGDMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21257470 | 0.73 | BIRC5 (0.47) | MGLLALOX5TP53ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093210-B2 | Treatment of sepsis with 5-ethyl-1-phenyl-2(1H)-pyridone | SOLANAN, INC. (US) | 2012-01-10 | — | — | US | disclosed |