Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMM2 | O15305 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059032 | 0.84 | COMT (0.49) | HSP90AA1L3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3302828 | 0.79 | ALDH1A1 (0.70) | HSP90AA1MGLLL3MBTL1ALDH1A1HPGD | |
| SCHEMBL2222230 | 0.78 | MGLL (0.50) | MGLLALDH1A1PMM2MPIPHOSPHO1 | |
| SCHEMBL9292198 | 0.78 | HSP90AA1 (0.49) | HSP90AA1MGLLL3MBTL1ALDH1A1HPGD | |
| SCHEMBL18050078 | 0.78 | MGLL (0.54) | MGLLALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL92819 | 0.78 | KDM4E (0.57) | MGLLALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL18050030 | 0.77 | FGFR1 (0.47) | L3MBTL1ALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL13907449 | 0.77 | KMT2A (0.53) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| Amphenidone SCHEMBL586236 | 0.77 | MAPT (0.57) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL13672252 | 0.77 | FAAH (0.52) | MGLLL3MBTL1ALDH1A1MPIALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138329-B1 | Composition containing 5-Methyl-1-phenyl-2-(1 H)-pyridone for reparation and prevention of fibrotic lesions | YAMAUCHI SHITOTOMO (JP) | 2004-06-02 | — | — | EP | claimed |
| EP-0383591-B1 | Use of 5-methyl-1-phenyl-2-(1H)-pyridone in the prevention of fibrotic lesions | YAMAUCHI SHITOTOMO (JP) | 2001-11-21 | — | — | EP | claimed |
| WO-2022081795-A9 | ON DEMAND AND LONG-TERM DRUG DELIVERY FROM DEGRADABLE NANOCAPSULES | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023091479-A1 | DETECTION AND TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS | AmMax Bio, Inc. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
| WO-2022081795-A2 | ON DEMAND AND LONG-TERM DRUG DELIVERY FROM DEGRADABLE NANOCAPSULES | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2022-04-21 | — | — | WO | disclosed |
| EP-3644983-A1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | Yale University (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20200016138-A1 | GEL CONTAINING PIRFENIDONE | EXCALIBUR PHARMACEUTICALS, INC. | 2020-01-16 | — | — | US | disclosed |
| WO-2019005816-A1 | COMPOSITIONS AND METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | YALE UNIVERSITY (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018236698-A1 | TRANSDERMAL CREAM FOR TREATING DUPUYTREN'S CONTRACTURE | Advanced Fibrosis Research LLC (US) | 2018-12-27 | — | — | WO | disclosed |
| US-20180360751-A1 | Transdermal cream for treating Dupuytren's Contracture | Advanced Fibrosis Research LLC (US) | 2018-12-20 | — | — | US | disclosed |
| EP-3102703-A2 | METHODS FOR TREATING FIBROTIC DISEASE | Effector Therapeutics Inc. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015191841-A1 | NOVEL METHODS OF TREATING OR PREVENTING FIBROTIC LUNG DISEASES | YALE UNIVERSITY (US) | 2015-12-17 | — | — | WO | disclosed |
| WO-2015120350-A2 | COMPOSITIONS AND METHODS FOR TREATING FIBROTIC DISEASE | EFFECTOR THERAPEUTICS, INC. (US) | 2015-08-13 | — | — | WO | disclosed |
| WO-2015118365-A1 | NOVEL USE OF SIGMA-1 RECEPTOR AGONIST COMPOUNDS | MTA TÁMOGATOTT KUTATÓCSOPORTOK IRODÁJA (HU) | 2015-08-13 | — | — | WO | disclosed |
| EP-2670242-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | Genoa Pharmaceuticals, Inc. (US) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012106382-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | GENOA PHARMACEUTICALS, INC. (US) | 2012-08-09 | — | — | WO | disclosed |
| EP-1261338-A4 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1261338-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | Cymar, Inc. (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001062253-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR, INC. (US) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200016138-A1 | GEL CONTAINING PIRFENIDONE | PIR, COL1A1, CUTA | HSP90AA1 110/4885MGLL 4261/4885L3MBTL1 4350/4885 |
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | HSP90AA1 4083/4885MGLL 1457/4885L3MBTL1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.