Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295496 | 1.00 | PGR (0.44) | PGRSLC6A4HTR6HTR2CHTR2B | |
| SCHEMBL31295473 | 0.86 | MAOB (0.42) | SLC6A4HTR6HTR2CMAOBALDH1A1 | |
| SCHEMBL16322050 | 0.77 | HTT (0.53) | PGRMETROCK2 | |
| SCHEMBL16322048 | 0.77 | HTT (0.53) | PGRMETROCK2 | |
| SCHEMBL17841289 | 0.73 | PGR (0.43) | PGRROCK2ALDH1A1 | |
| SCHEMBL18898417 | 0.70 | PGR (0.39) | PGRROCK2 | |
| SCHEMBL17857556 | 0.70 | PGR (0.42) | PGRROCK2 | |
| SCHEMBL17861559 | 0.69 | PGR (0.40) | PGRTHRBROCK2ALDH1A1 | |
| SCHEMBL16324040 | 0.69 | SMN1; SMN2 (0.69) | ALDH1A1 | |
| SCHEMBL16324039 | 0.69 | SMN1; SMN2 (0.69) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118931-A | Barbituric acid derivative and preparation method thereof | 武汉绿合医药科技有限公司 | 2024-12-13 | — | — | CN | disclosed |