Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 12/20 | 0.34 |
| ▸ | CA1 | P00915 | 11/20 | 0.34 |
| ▸ | CA9 | Q16790 | 10/20 | 0.34 |
| ▸ | CA12 | O43570 | 8/20 | 0.34 |
| ▸ | CA5A | P35218 | 5/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276878 | 0.85 | KDM4E (0.38) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL21918985 | 0.82 | KDM4E (0.42) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL3989665 | 0.80 | KDM4E (0.41) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL2654567 | 0.80 | KDM4E (0.45) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL14612384 | 0.80 | KDM4E (0.41) | KDM4EPKMALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL27764055 | 0.78 | KDM4E (0.44) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL31664536 | 0.77 | KDM4E (0.38) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL415794 | 0.74 | KDM4E (0.36) | KDM4EPKMALDH1A1MEN1LMNA | |
| SCHEMBL15653253 | 0.72 | KDM4E (0.39) | KDM4EPKM | |
| SCHEMBL539978 | 0.70 | KDM4E (0.33) | KDM4EPKMALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109563-A1 | SPIRO-HYDANTOIN DERIVATIVE EXHIBITING ADAMTS-4 INHIBITORY ACTIVITY, AND USE THEREOF | 서울대학교병원 | 2025-05-30 | — | — | WO | claimed |
| CN-109054648-A | Serosity combination for chemically mechanical polishing | LTCAM有限公司 | 2018-12-21 | — | — | CN | claimed |
| EP-4580601-A1 | PHARMACEUTICAL COMPOSITIONS FOR HERPES VIRUS | Assembly Biosciences, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025046456-A1 | A CRYSTALLINE FORM OF 2-(3-(2,,5'-DIFLUORO-[1,1'-BIPHENYL]-4-YL)-2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)-4-METHYLTHIAZOLE-5-SULFONAMIDE | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025046457-A1 | A CRYSTALLINE FORM OF 2-(3-(2,,5'-DIFLUORO-[1,1'-BIPHENYL]-4-YL)-2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)-4-METHYLTHIAZOLE-5-SULFONAMIDE | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024047508-A1 | PHARMACEUTICAL COMPOSITIONS FOR HERPES VIRUS | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| US-20230104936-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. | 2023-04-06 | — | — | US | disclosed |
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2010045580-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | EXELIXIS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| EP-0847391-B1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2001-12-19 | — | — | EP | disclosed |
| US-6100258-A | 6-(N-(5-BROMO-2-(2-METHYLPROP-2-EN-1-YLOXY)BENZYL)-N -ETHYLAMINO)-PYRIDAZIN-3-YLCARBOXYLIC ACID, AND OTHER 3,6-DISUBSTITUTED PYRIDAZINE DERIVATIVES OF SPECIFIED FORMULA; RELIEVING PAIN | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230104936-A1 | TRPML MODULATORS | TRPM2, TRPM4, TRPM5 | KDM4E 2480/4885PKM 527/4885ALDH1A1 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.